Stiles had suffered from superior dementia and prostate most cancers.
An announcement from the Stiles household learn: “The Stiles household are unhappy to announce that Nobby Stiles handed away peacefully in the present day surrounded by his household after an extended sickness.
“The household kindly ask for privateness at this unhappy time.”
Stiles made 28 worldwide appearances for England and was a part of the 1966 successful squad.
He additionally received two league titles and the 1968 European Cup throughout his 11-year spell with United.
The England nationwide workforce paid tribute to Stiles on social media: “We’re extremely saddened to be taught of the passing of Nobby Stiles, a key member of our @FIFAWorldCup successful squad, on the age of 78.
“All of our ideas are with Nobby’s family members.”
Manchester United additionally launched an announcement which learn: “We’re extraordinarily saddened to be taught of the passing of Nobby Stiles MBE.
“An integral a part of our first-ever European Cup-winning aspect, Nobby was a titan of the membership’s historical past, cherished for his coronary heart and character on and off the pitch. He will likely be sorely missed by us all.”